The City of Apopka is located in northwest Orange County Florida. Businesses in the City are served by major roadways, rail and airports. The recently completed Western Beltway (State Road 429) and US 441 provide easy access to the Florida Turnpike, I-75, SR 408 and I-4.
Two international airports are located close to the City, the Orlando International Airport and the Orlando-Sanford Airport both within 26 miles. The City also has its own regional airport, located on the west side along US 441.
Page info taken from : http://www.apopka.net/ecdev/01c_location.html